Pathophysiologic Treatment Approach to Irritant Contact Dermatitis

Allergic and Irritant Contact Dermatitis

Wound-Related Allergic/Irritant Contact Dermatitis.

PURPOSE To provide information from a literature review about the prevention, recognition, and treatment for contact dermatitis. TARGET AUDIENCE This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES After participating in this educational activity, the participant should be better able to:1. Identify signs and symptoms o...

Cytokines and Chemokines in Irritant Contact Dermatitis

Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences bet...

Current concepts of irritant contact dermatitis.

Correspondence to: Dr J S C English, Consultant Dermatologist, Queen’s Medical Centre, University Hospital, Nottingham NG7 2UH, UK; john.english@ mail.qmcuh-tr.trent.nhs.uk _________________________ C ontact dermatitis is an eczematous eruption caused by external agents, which can be broadly divided into irritant substances that have a direct toxic effect on the skin (irritant contact dermatiti...

Irritant Contact Dermatitis from Jet Fuel

A previously healthy 31-year-old man presented to the emergency department complaining of right foot pain and a non-pruritic rash with swelling for one day. He reported spilling jet fuel on his right lower leg at work the previous evening and had worn the fuel-soaked sock for another 10 hours. Physical examination demonstrated a coalescing erythematous macular rash with mild non-pitting edema i...